Alexandros D. Κiparissides
Assistant Professor, Biochemical Engineering

– Ph.D. Chem. Eng. (Imperial College, UK, 2012)
– Dipl. Chem. Eng. (AUTh, GR, 2006)

Curriculum vitae


Office: 306, 3rd floor, Building D
Student Reception: Daily 9:30 – 16:00 or with prior appointment

Development of combined mathematical and experimental approaches for the multi-scale analysis of industrial bioprocesses with a focus on recombinant protein production in mammalian cell culture systems and the use of microalgae for the production of biofuels, high-value chemicals and the biodegradation of toxic compounds.

  1. Characterisation and analysis of cell metabolism under industrial bioprocessing conditions
  2. Systems Biology and Metabolic Modelling
  3. Design of Experiments
  4. Development of mathematical models and model analysis techniques (Parameter Estimation, Sensitivity Analysis) to facilitate the model-based design and optimisation of industrial scale bioprocesses
  1. Kiparissides A., Kucherenko S., Mantalaris A., Pistikopoulos E.N. (2009). Global Sensitivity Analysis Challenges in Biological Systems Modeling. Ind. Eng. Chem. Res., v.48(15), pp: 7168–7180.
  2. Koutinas M., Kiparissides A., Silva-Rocha R., Lam M.C., Martins dos Santos V., de Lorenzo V., Pistikopoulos E.N. and Mantalaris A. (2011). Linking Genes to Microbial Growth Kinetics – An Integrated Biochemical Systems Engineering Approach. Metabolic Engineering, v.13(4), pp: 401-13.
  3. Kiparissides A., Pistikopoulos E.N., Mantalaris A. (2015). On the Model Based Optimisation of Monoclonal Antibody Production in GS-NS0 Cell Cultures. Biotechnology & Bioengineering, v.112(3), pp: 536-548
  4. Kiparissides A., Hatzimanikatis V. (2017). Thermodynamics-based Metabolite Sensitivity Analysis in Metabolic Networks. Metabolic Engineering, v.39, pp: 117-127
  5. Lularevic M., Racher A.J., Jaques C., Kiparissides A. (2019). Improving the accuracy of flux balance analysis through the implementation of carbon availability constraints for intracellular reactions. Biotechnology & Bioengineering, v.116(9), pp: 2339-2352
  1. Chemical Reactor Design I (ΧΑ6)
  2. Chemical Reactor Design II (ΧΑ7)