Alexandros D. Κiparissides
Assistant Professor, Biochemical Engineering

– Ph.D. Chem. Eng. (Imperial College, UK, 2012)
– Dipl. Chem. Eng. (AUTh, GR, 2006)

Curriculum vitae

 

Contact
Office: 306, 3rd floor, Building D
Telephone:2310.995917
Email: alexkip@auth.gr
WWW: https://lbe.cheng.auth.gr/
Student Reception: Daily 9:30 – 16:00 or with prior appointment

Development of combined mathematical and experimental approaches for the multi-scale analysis of industrial bioprocesses with a focus on recombinant protein production in mammalian cell culture systems and the use of microalgae for the production of biofuels, high-value chemicals and the biodegradation of toxic compounds.

  1. Characterisation and analysis of cell metabolism under industrial bioprocessing conditions
  2. Systems Biology and Metabolic Modelling
  3. Design of Experiments
  4. Development of mathematical models and model analysis techniques (Parameter Estimation, Sensitivity Analysis) to facilitate the model-based design and optimisation of industrial scale bioprocesses

Booth M., Spicer A., Kiparissides A. (2021). Shedding light on phototrophic biomass production of Chlorella variabilis: The importance of dissolved CO2, light intensity and duty cycle . Biochemical Engineering journal, v.179

Sanchez-Tarre V., Kiparissides A. (2021). The effects of illumination and trophic strategy on gene expression in Chlamydomonas reinhardtii . Algal Research, v.54

Lularevic M., Racher A.J., Jaques C., Kiparissides A. (2019). Improving the accuracy of flux balance analysis through the implementation of carbon availability constraints for intracellular reactions . Biotechnology & Bioengineering, v.116(9), pp: 2339-2352

Kiparissides A. , Hatzimanikatis V. (2017). Thermodynamics-based Metabolite Sensitivity Analysis in Metabolic Networks . Metabolic Engineering, v.39, pp: 117-127

Kiparissides A. , Pistikopoulos E.N., Mantalaris A. (2015). On the Model Based Optimisation of Monoclonal Antibody Production in GS-NS0 Cell Cultures . Biotechnology & Bioengineering, v.112(3), pp: 536-548 

  1. Chemical Reactor Design Ι (ΧΑ6, 6th semester – compulsory)
  2. Chemical Reactor Design IΙ (ΧΑ7, 7th semester – compulsory)
  3. Biochemical Engineering (ΒΤ8, 8th semester – compulsory)
  4. Pharmaceutical product manufacturing (MSc Chemical and Biochemical Engineering: Food & Healthcare)
1. Antonia Papadopoulou, «Development of a continuous fermentation process for plasmid DNA manufacturing», (Start date: November 2023).
2. Nikos Stratis, «Digitalisation of a continuous plasmid DNA manufacturing process through an integrated supervisory control and hybrid modelling approach», (Start date: December 2023).
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